The dried out leaves and blossoms are also smoked to soothe epilepsy. The leaves as well as flowers are reported to produce a mild blissful result when smoked and have actually been claimed to have a similar, although less powerful, psychoactive impact to marijuana. To join together the botanical aspects, ethnopharmacology, phytochemistry, organic activity, toxicity as well as commercial elements of the clinical literary works readily available on Leonotis leonurus. Leonotis leonurus has generally terpenoids, specifically labdane diterpenes, the major diterpene reported is marrubiin. Different various other substances have been reported by some authors to have been separated from the plant, including, in the preferred literature only, the mildly psychedelic alkaloid, leonurine. Leonurine has nonetheless, never ever been reported by any kind of clinical analysis of the removes of L. leonurus. In spite of the publication of numerous papers on L. leonurus, there is still, nonetheless, the need for clear-cut research study and also clarification of other compounds, consisting of alkaloids and also important oils from L. leonurus, in addition to from various other plant components, such as the origins which are extensively made use of in typical medicine. The traditional use by smoking cigarettes additionally requires more examination regarding exactly how the chemistry as well as activity are influenced by this type of management. Research study has proven the psychoactive impacts of the unrefined remove of L. leonurus, but verification of the visibility of psychedelic compounds, as well as seclusion and also characterisation, is still needed. Purposeful deterioration of L. leonurus with synthetic cannabinoids has been reported recently, in an attempt to facilitate the advertising and marketing of these illegal compounds, highlighting the requirement for improvement of ideal quality assurance procedures to guarantee security as well as quality. Much work is consequently still called for on the facet of quality control to make certain safety, high quality as well as efficiency of the product provided to patients, as this plant is widely used in South Africa as a traditional medication. Readily available plant resources provide a feasible option for phytochemical research study, particularly when it come to the proper validation of the plant product in order to identify and also delimit closely related varieties such as L. leonurus and L. nepetifolia which are very comparable in routine.